You use profound to emphasize that something is very great or intense. [emphasis] 深刻的；强烈的；巨大的；
//…discoveries which had a profound effect on many areas of medicine.
对很多医学领域产生了深刻影响的发现
//…profound disagreement…
严重的分歧
The overwhelming feeling is just deep, profound shock and anger…
最强烈的感觉就是深深的震惊和愤怒。
Anna’s patriotism was profound.
安娜有强烈的爱国心。
showing great knowledge or understanding 知识渊博的；理解深刻的；深邃的
profound insights
精辟的见解
a profound book
深奥的书